Hair Loss in Men

Hair loss in men with a genetic predisposition to male pattern baldness is a form of hair loss associated with male hormones. It affects 80% of men who reach the age of 80. Genetic, structural (testosterone hormone) and environmental factors (smoking, inappropriate diets, stress and sedentary lifestyle) play a role in the pathogenesis. It has been shown that genetically increased production of some microRNAs may play a role in the pathogenesis of male pattern baldness. It is known that chronic inflammation in the hair follicle also plays a role in the pathogenesis of male pattern baldness.

Male pattern hair loss is classified by norwood

Hair loss in middle-aged men is a very common problem. Studies have shown that the problem of hair loss affects 50% of men over 40. In most cases, hair loss is permanent. If you are also experiencing hair loss problem, do not despair. There are several methods recommended by modern medicine to prevent hair loss.

Temporary hair loss in men can be easily treated. According to experts; Hair loss can be easily prevented in men who lose their hair due to a disease, malnutrition, stress and unhealthy living conditions. When men who lose their hair due to certain diseases are treated, hair loss can stop. Likewise, hair loss due to stress, unhealthy living conditions and malnutrition can be stopped when these conditions are removed. For men with permanent hair loss, the most recommended method is FUE.

Causes of Hair Loss in Men

Another reason for hair loss in men is that male hormones are thought to act on the dermal papilla cells located in the roots of the hair. The dermal papilla cells in balding individuals contain more male hormone receptors. Genetically sensitive dermal papilla cells on the scalp are activated by male hormones and hair loss begins. In general, it has not been fully resolved how hormones that stimulate growth paradoxically initiate hair loss. When the muscles in the neck and forehead are constantly active, there is a decrease in the blood flow to the scalp. With the decrease in the amount of incoming blood, the decreased oxygen levels increase the conversion of the male hormone to a more active form, which leads to hair loss.

Main Factors for Hair Loss in Men

The nicotine in cigarettes can increase the problem of hair loss in men by increasing carbon monoxide in the blood and causing narrowing of the vessels. The “p substance” that increases in stress accelerates the entry of the hair into the catagen phase. Hair loss disorders such as alopecia areata, telogen effluvium and trichotillomania are also associated with stress.

In improper diets, vitamin A (a powerful antioxidant that increases sebum production in the skin), vitamin C (antioxidant), vitamin E (a strong antioxidant that increases dermal blood circulation), biotin 8 increases keratin production, inositol (effective at cellular level), niacin (in the scalp). Not taking vitamins, amino acids and minerals such as blood circulation increases) can also lead to hair loss in men. With this type of loss, the follicles of the large terminal hair progressively shrink into very fine hairs. This thinning cannot be explained solely by the progressive shortening of the anagen cycles. Because if it were together with the shortening of anagen cycles, it would be expected to take a very long time. There are studies showing that miniaturization may be in the form of a sudden and large decrease in the cells in the follicle and shrinkage of the dermal papilla in a single step.

The primary follicles in the center are surrounded by smaller peripheral secondary hair follicles. Each follicular unit is supported by the erector pili, which surrounds the primary follicle and wraps around the secondary follicles to varying degrees. Male pattern baldness is seen in different patterns in males and females, while sensitive follicles in the scalp undergo miniaturization in a different and reproducible manner. In women with male pattern baldness, the number of follicular units does not decrease, but the hair in the follicular unit decreases. Studies are continuing on the effects of molecules such as nerve growth factor (NGF), which increases cell proliferation, heparanz, which destroys the extracellular matrix, thymosin beta 4, which is an important mediator on cell migration, angiogenesis and wound healing, and endoglycosidase, on hair loss and hair growth.

Causes of Hair Loss in Men

While hair loss in men negatively affects the quality of life, it can lead to psychological and social problems. Patients who lose their hair either accept this situation or seek treatment methods. Young people who accept the situation they are in are not directed to treatment methods because they do not get too stressed. Scientific studies are being conducted on the relationship of this condition with benign prostate enlargement, prostate cancer, cardiovascular diseases and scalp cancer.